- Stock #3062-0 (326.5 grams)
Collatrim Plus is a unique protein supplement formulated to support the collagen structures of the body and help improve joint health. Collatrim Plus, as a rich source of protein, may also enhance skin health and tone, as well as facilitate weight management by promoting the growth of lean muscle tissue.
Collatrim Plus provides a rich source of protein derived from hydrolyzed bovine collagen. Protein supplements comprised of hydrolysates, or predigested proteins, supply amino acids in a form that is readily absorbed into the body’s protein stores. Protein is required for a myriad of body functions, including the formation, maintenance and repair of blood, bone, muscle, skin, and internal organs, as well as the production of hormones and enzymes. Thus, protein deficiency can lead to numerous health problems, including fatigue and weakness, mental depression, lowered resistance to colds and infections, impaired wound healing, and loss of muscle and skin tone. Experimental and clinical data also indicate that low protein intake negatively affects bone health—protein deficiency causes a rapid alteration in bone mass and strength and inhibits the synthesis of bone-matrix proteins, which can lead to decreased bone mineral density and the development of osteoporosis.1-8
3,9-15– Collagen is the most abundant protein in the body and is essential for maintaining the health and strength of connective tissues such as cartilage. Hydrolyzed collagen has been shown to have an anabolic (building-up) effect on cartilage tissue. Research indicates that orally ingested hydrolyzed collagen accumulates in cartilage and stimulates a statistically significant increase in the production of extracellular matrix components that form cartilage. A review of double-blind studies confirmed that hydrolyzed collagen can provide improvement in joint pain and function in some men and women with osteoarthritis. Results from a 6-month study found that hydrolyzed collagen provided statistically significant changes in various parameters of joint pain compared to placebo, and thus, may prove beneficial for supporting joint health in patients with osteoarthritis. Hydrolyzed collagen may also help reduce the risk of joint deterioration among high-risk individuals. In addition, hydrolyzed collagen has been shown to significantly decrease pain levels in patients with medically-diagnosed fibromyalgia and concurrent temporomandibular joint problems.
Collagen makes up roughly 70-80% of the dry weight of skin and provides the skin’s strength and structural integrity. Adequate protein intake is essential for skin health and proper wound healing. Thus, protein deficiency, which reduces collagen synthesis, can result in poor wound repair, as well as loss of muscle and skin tone. For example, a study on wound healing found that patients taking a hydrolyzed collagen supplement experienced approximately twice the rate of healing of pressure ulcers compared to those given a placebo.3,9,10,16-20
Furthermore, hydrolyzed collagen provides certain amino acids that may enhance the building of lean muscle mass and promote weight-loss. For example, the amino acid arginine enhances weight-loss and muscle building by promoting fat metabolism and the production of growth hormone—increasing growth hormone production in adults has been shown to enhance the breakdown of fat stores and the building and toning of muscle tissue. Likewise, the amino acid glycine has also been shown to stimulate the release of growth hormone, and, in conjunction with arginine, is utilized for the production of creatine—increasing levels of creatine in the body has been shown to improve lean muscle mass and strength and to reduce the degeneration of muscle tissue, which is characteristic of low-protein intake.4,6,21-28
Collatrim Plus also contains concentrated Aloe vera (Aloe barbadensis).
Aloe barbadensis) supplies many nutrients, including vitamins C and E and the minerals calcium, silicon and zinc. These important nutrients are essential for the health and integrity of connective tissues. In fact, aloe vera has been shown to stimulate connective tissue and epidermal growth and repair, and has been used for decades, both internally and externally, to enhance wound healing and promote skin health.1,9,17(
1Talbott, S.M. & Hughes, K. The Health Professional’s Guide to Dietary Supplements. Lippincott Williams & Wilkins; 2006.
2Cohen, E. “Are You Eating Enough Protein?“ Delicious! Magazine; November 1996.
3McFarland, J. L. Aging Without Growing Old. Palos Verdes, CA: Western Front Ltd, 1997.
4Balch, J. Prescription for Nutritional Healing. Garden City Park, NY: Avery Publishing Group, 1990.
5Gaby MD, A. “Dietary protein and osteoporosis.“ American Journal of Natural Medicine; 1998, 5(7):11.
6Chaitow DO, L. Thorsons Guide To Amino Acids. London: Thorsons, 1991.
7Dunne, L.J. Nutrition Almanac, 3rd Ed. NY, NY: McGraw-Hill Publishing Co.; 1990.
8Bonjour JP. “Dietary protein: an essential nutrient for bone health.“ Journal of the American College of Nutrition; 2005, 24(6 Suppl):526S-536S.
9Murray ND, M. The Healing Power of Herbs. Rocklin, CA: Prima Publishing, 1995.
10Murray ND, M. & Pizzorno ND, J. Encyclopedia of Natural Medicine, 2nd Ed. Rocklin, CA: Prima Publishing, 1998.
11Clark, K.L., et. al. “24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain.“ Current Medical Research and Opinion; 2008, 24(5):1485-96.
12Aigner, T. & Stöve, J. “Collagens–major component of the physiological cartilage matrix, major target of cartilage degeneration, major tool in cartilage repair.“ Advanced Drug Delivery Reviews; 2003, 55(12):1569-1593.
13Bello, A.E. & Oesser, S. “Collagen hydrolysate for the treatment of osteoarthritis and other joint disorders: a review of the literature.“ Current Medical Research and Opinion; 2006, 22(11):2221-2232.
14Moskowitz, R.W. “Role of collagen hydrolysate in bone and joint disease.“ Seminars in Arthritis and Rheumatism; 2000, 30(2):87-99.
15Olson, G.B., et. al. “The effects of collagen hydrolysat on symptoms of chronic fibromyalgia and temporomandibular joint pain.“ Cranio: The Journal of Craniomandibular Practice; 2000, 18(2):135-141.
16Oikarinen, A. “Aging of the skin connective tissue: how to measure the biochemical and mechanical properties of aging dermis.“ Photodermatology, Photoimmunology & Photomedicine; 1994, 10(2):47-52.
17MacKay, D. & Miller, A.L. “Nutritional support for wound healing.“ Alternative Medicine Review; 2003, 8(4):359-377.
18Kulozik, M. & Krieg, T. [Changes in collagen connective tissue and fibroblasts in aging]. Zeitschrift für Hautkrankheiten; 1989, 64(11):1003-1004, 1007-1009.
19Uitto, J. “Connective tissue biochemistry of the aging dermis. Age-related alterations in collagen and elastin.“ Dermatologic Clinics; 1986, 4(3):433-446.
20Lee, S.K., et. al. “Pressure ulcer healing with a concentrated, fortified, collagen protein hydrolysate supplement: a randomized controlled trial.“ Advances in Skin & Wound Care; 2006, 19(2):92-96.
21Taffin, A. & Pluvinet, R. “Hydrolyzed collagen.“ Wellness Foods Europe; November 2006.
. Accessed August 2008.
22Crayhon, R. “Nutrition in the 21st Century.“ Nutrition Science News; June 1995.
23Null PhD, G. The Clinician’s Handbook of Natural Healing. NY, NY: Kensington Books, 1997.
24Hackman PhD, R. “Creatine for Athletic Enhancement.“ Nutrition Science News; July 1996.
25Jones, D. Nutrition and Cancer. 1992.
26Klatz, R. Grow Young with HGH. NY, NY: HarperCollins, 1997.
27Visek WJ. “Arginine needs, physiological state and usual diets. A reevaluation.“ Journal of Nutrition; 1986, 116(1):36-46.
28Kasai, K., et. al. “Glycine stimulated growth hormone release in man.“ Acta Endocrinologica; 1980, 93(3):283-286.